METABOLIC SYNDROM AND RISK FACTORS OF ATHEROSCLEROSIS IN YOUNG CZECH POPULATION
Aim: Atherosclerosis is a chronic disease of blood-vessel wall proceeding for long time asymptomaticly. There are atherosclerosis lesions type I-II (foam cells and fatty streak) in 60% of adolescents. The aim of this work is to determine incidence of risk factors of atherosclerosis and metabolic syndrom.
Methods: Casual BP, ABPM, antropometric parametrs and laboratory values were determined.
Results: Total 276 participants (51% of women) age 23,8±3,6 years. Hypertension was diagnosed according to casual BP in 25,4% of persons (28,9% of men and 22,7% of women), according to ABPM in 28,3% of persons (37,8% of men and 19,1% of women). Casual hypertension was verified by ABPM in 17,0% of men and in 12,1% of women. There were 5,9% of men and 12,1% of women smoking. Overweight (BMI 27 - 29,9) had 2,2 % of persons, obesity 1st degree (BMI 30 - 34,9) had 0,7 % of persons. No man had waist-hip ratio above 1,0 and 2 women (1,4 %) had WHR above 0,85. Total 2,2 % men had girth above 102 cm and none of the women had girth above 88 cm. Cholesterol>5 mmol/l had 24,4% of persons, LDL>3 mmol/l had 16,8% of persons, triglycerides>2 mmol/l had 4,4% of persons, HDL < 1 mmol/l had 8 % of men, HDL < 1,2 mmol/l had 2,3% of women. Young women had significantly higher total cholesterol and HDL. Men with positive family history had significantly higher pulse pressure, women had higher systolic, diastolic and pulse pressure and lower HDL. Men with hypertension had lower HDL. Total 2,7% of participants had glycemia 6,1-7,0 mmol/l.
Conclusion: Metabolic syndrom was diagnosed in 3 men and 2 women. There is high prevalence of hypertension, low prevalence of smoking and obesity. Women in young age had more suitable lipid spectrum. Sportsmen had lower diastolic BP, higher HDL and lower LDL.Positive family history is risk factor for BP and lipid spectrum.